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The information on this website is designed to offer self-care tips and recommendations based on evidence-based research and literature from professionals in each field. It is not intended to diagnose or treat any specific medical condition. Please consult with your healthcare provider before making any health-related decisions.
Combining these two natural supplements can help you fall asleep quickly and stay asleep by calming the parts of the brain that prevent sleep. Numerous studies have shown that both apigenin and magnesium L-threonate promote a natural intervention supporting sleep quality. In this article, I’ll explain how these supplements target specific brain areas that may interfere with sleep and explore their unique mechanisms in preventing wakefulness.
What Are Apigenin and Magnesium L-Threonate?
Apigenin and magnesium L-threonate are nutraceuticals, which are plant- and food-derived compounds known for their health benefits.
- Apigenin is found in various plants, vegetables, fruits, and spices. It helps protect plants against harmful UV radiation and diseases. Studies in human consumption have shown that apigenin not only improves sleep but can treat depression, anxiety, cancer, Alzheimer’s disease, and dementia. It also improves cognition, learning, memory, and insomnia.
- Magnesium L-threonate is a form of magnesium present in many plant foods, supporting plant growth and development. Similar to apigenin, magnesium L-threonate has been shown to benefit human health by treating various cognitive dysfunctions, mental disorders, and sleep disorders.
How Do These Compounds Promote Sleep?
Sleep is regulated by a balance between sleep-promoting and wake-promoting neurons in the brain. Sleep difficulties often arise when wake-promoting neurons are too active while sleep-promoting neurons are not sufficiently active. These supplements help restore this balance.
- Apigenin works by targeting multiple receptors in the brain that can keep the mind active, especially in cases of anxiety or depression. By calming these receptors, apigenin allows sleep-promoting neurons to function more effectively, aiding in falling and staying asleep. Additionally, apigenin has anti-inflammatory properties, reducing oxidative stress and helping the brain function properly.
- Magnesium L-threonate may enhance sleep quality by reducing anxiety and promoting relaxation. It modulates the activity of neurotransmitters like gamma-aminobutyric acid (GABA), which has calming effects on the nervous system. GABA helps inhibit neuronal firing, often heightened in people who have trouble falling asleep.
Whether you’re dealing with anxiety, depression, or a racing mind that keeps you awake, these natural substances help calm the brain areas responsible for these sleep-preventing activities, aiding in both falling and staying asleep.
Dosage and Timing to Support Sleep
For improved sleep, most studies recommend taking 150 mg to 500 mg of Apigenin and 350-450 mg of Magnesium L-threonate daily. These supplements should be taken 30-60 minutes before bedtime. The time needed to see results can vary, with some people noticing improvements within a few days and others taking a few weeks.
Apigenin and magnesium L-threonate offer a natural and effective approach to improving sleep quality. By targeting specific receptors and neurotransmitters in the brain, these supplements help calm overactive wake-promoting neurons and support sleep-promoting processes. Whether you’re struggling with anxiety, depression, or simply a busy mind that prevents you from sleeping, these natural compounds can be a valuable addition to your nightly routine. As with any supplement, it’s essential to consult a healthcare professional to ensure it fits your individual health needs. Please review the disclaimer at the top of this page. Consistent use of apigenin and magnesium L-threonate may provide a gentle, natural way to achieve better sleep and overall well-being.
